The First and Second Cluster Analysis of Dual Index Grade Sequence of IR Fingerprint Spectra of Guifudihuang Pill and Jinkuishenqi Pill Samples and Their Quality Evaluation
ZOU Hua-bin1,HAN Zhi-feng1,ZHAI Hong2,WEI Ying-qin3,WANG Fei1
1. School of Chemistry and Chemical Engineering of Shandong University (East Campus), Ji’nan 250100, China 2. Shandong Province Hospital, Ji’nan 250021, China 3. Department of Chemical Engineering, Shandong Institute of Light Industry, Ji’nan 250100, China
Abstract:In the present paper a method for identifying and evaluating traditional Chinese medicine(TCM) Jinkuishenqi pill and Guifudihuang pill samples is proposed. Mathematical statistics was applied to analyze the dual index sequences of infrared fingerprint spectra of components extracted from Jinkuishenqi pill and Guifudihuang pill samples with water, then the grade sequences were determined and the first and second clusters were performed based on these grade sequences. As a results, the most similar sample groups of different samples were also obtained. The Jinkuishenqi pill and Guifudihuang pill samples can be distinguished accurately with the most similar sample groups. The method put forward is new and effective to identify and evaluate combinational TCM quantitatively.
Key words:Combinational TCM;Guifudihuang Pill;Jinguishenqi Pill;Infrared fingerprint spectra;Sequence analytical method;First and second cluster;Quality evaluation
邹华彬1,韩智峰1,翟 红2,魏英勤3,王飞1 . 桂附地黄丸金匮肾气丸指纹图谱双指标等级序列二次聚类分析及质量评价[J]. 光谱学与光谱分析, 2007, 27(12): 2432-2436.
ZOU Hua-bin1,HAN Zhi-feng1,ZHAI Hong2,WEI Ying-qin3,WANG Fei1. The First and Second Cluster Analysis of Dual Index Grade Sequence of IR Fingerprint Spectra of Guifudihuang Pill and Jinkuishenqi Pill Samples and Their Quality Evaluation. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2007, 27(12): 2432-2436.
[1] Zou Huabin, Yang Guosheng, Qin Zhengran, et al. Analytical Letters, 2005, 38(9): 1457. [2] ZOU Hua-bin, YUAN Jiu-rong(邹华彬,袁久荣). World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica(世界科学技术-中医药现代化), 2003,5(4):36. [3] ZOU Hua-bin, YUAN Jiu-rong, DU Ai-qin, et al(邹华彬, 袁久荣, 杜爱琴,等). Chinese Traditional Patent Medicine(中成药), 2004, 26(10): 779. [4] ZOU Hua-bin, YUAN Jiu-rong, DU Ai-qin, et al(邹华彬, 袁久荣, 杜爱琴,等). China Journal of Chinese Materia Medica(中国中药杂志),2005,30(1):16. [5] Zou Huabin, Yuan Jiurong, Du Aiqin, et al. Analytical Letters, 2005, 38(7): 1167. [6] Zou Huabin, Yang Guosheng, Du Aiqin, et al. Biomedical Chromatograph, 2006, 20(6-7): 642. [7] ZOU Hua-bin, YUAN Hao, WANG Ai-wu, et al(邹华彬,袁 浩,王爱武,等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2007,27(9):1815. [8] DONG Bin, SUN Su-qin, ZHOU Hong-tao, et al(董 彬,孙素琴,周红涛,等). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2002,22(2):232. [9] ZHOU Qun, SUN Su-qin, LIANG Xi-yun(周 群,孙素琴,梁曦云). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2003,23(3):509. [10] CHENG Cun-gui, YING Tao-kai(程存归,应桃开). Spectroscopy and Spectral Analysis(光谱学与光谱分析),2005,25(1):36. [11] ZOU Hua-bin, YUAN Jiu-rong, WANG Wei(邹华彬,袁久荣,王 伟). World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica(世界科学技术-中医药现代化),2004,6(2):50. [12] ZHANG Shu-yu(张淑玉). Chinese Journal of Clinical Medicine(中国现代临床医学),2005,4(6):48. [13] DU Su-lan, GENG Ai-ping, LIU Yong-zhong(杜素兰,耿爱萍,刘永忠). Chinese Traditional Patent Medicine(中成药), 2001,23(11): 837.