1. School of Materials Science and Technology, China University of Geosciences, Beijing 100083, China 2. College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China 3. School of Stomatology, Peking University, Beijing 100081, China
Abstract：In the present work, 20 patients with salivary pleomorphic adenoma were recruited for FTIR spectroscopic measurement. These obtained FTIR spectra were analyzed and compared. It was found that there were significant differences in the spectral features of the skin covering normal salivary gland, pleomorphic adenoma, and carcinoma change of pleomorphic adenoma，such as the changes in peak position, band shape and relative intensity of the bands in the ranges of 1 000-1 800 cm-1 and 2 800-3 000 cm-1. Pathological diagnosis demonstrated that 2 of the 20 patients suffered actually carcinoma change of pleomorphic adenoma, which is in good agreement with the result of FTIR spectroscopic measurement. FTIR spectroscopic method suggested that pleomorphic adenoma is the intermediate between normal salivary gland and carcinoma change of pleomorphic adenoma.
Key words：FTIR;Mid-IR fiber optics;Pleomorphic adenoma;Non-invasive detection in vivo
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