Study on the Application of Empirical Mode Decomposition to Noninvasive Hemoglobin Measurement by NIRS
FAN Yi-chen1, 2, LU Qi-peng1*, DING Hai-quan1, GAO Hong-zhi1, CHEN Xing-dan1
1. State Key Lab of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China 2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China
Abstract:To increase the signal-to-noise ratio (SNR) of human near infrared (NIR) spectra, so as to improve the stability and precision of calibration model, the empirical mode decomposition (EMD) method was applied. Eighty-one fingertip absorption curves were collected, with the corresponding clinical examination results obtained immediately. By means of outliers detection and removal, finally 78 samples were determined as the research objects. A three-layer back-propagation artificial neutron network (BP-ANN) model was established and worked for prediction. The results turned out that, through EMD method, the prediction correlation coefficient increased greatly from 0.74 to 0.87. RMSEP was reduced from 12.85 to 8.08 g·L-1. Other indexes were also obviously improved. The overall results sufficiently demonstrate that it is feasible to use EMD method for high SNR pulse wave signals, thus improving the performance of noninvasive hemoglobin calibration models. The application of EMD method can help promote the development of noninvasive hemoglobin monitoring technology.
樊奕辰1, 2,卢启鹏1*,丁海泉1,高洪智1,陈星旦1 . 经验模态分解法在近红外无创血红蛋白检测中的应用研究[J]. 光谱学与光谱分析, 2013, 33(02): 349-353.
FAN Yi-chen1, 2, LU Qi-peng1*, DING Hai-quan1, GAO Hong-zhi1, CHEN Xing-dan1 . Study on the Application of Empirical Mode Decomposition to Noninvasive Hemoglobin Measurement by NIRS. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2013, 33(02): 349-353.
[1] Timm U, Lewis E, McGrath D, et al. Procedia Engineering, 2010, 5: 488. [2] Zhou Y, Zheng C, Cao H, et al. Biochemical and Biophysical Research Communications, 2012, 420: 205. [3] Causey M W, Miller M D S, et al. The American Journal of Surgery, 2011, 201: 592. [4] Jeon Kyejin, Kim Sujin, Park kunkook. Journal of Biomedical Optics, 2002, 7(1): 45. [5] LU Qi-peng, CHEN Cong, PENG Zhong-qi(卢启鹏,陈 丛,彭忠琦). Optics and Precision Engineering(光学精密工程), 2012, 20(4): 873. [6] CHEN Xing-dan(陈星旦). Optics and Precision Engineering(光学精密工程), 2008, 16(5): 759. [7] LU Wan-zhen(陆婉珍). Modern Near-Infrared Spectroscopy Analytical Technology, 2nd ed(现代近红外光谱分析技术,第2版). Beijing: China Petrochemical Press(北京:中国石化出版社), 2006. [8] CHEN Cong, LU Qi-peng, PENG Zhong-qi(陈 丛,卢启鹏,彭忠琦). Acta Optica Sinica(光学学报), 2012, 32(5): 0530001-1. [9] Huang N E, Shen Z, Long S R, et al. Proceedings of the Royal Society A, 1998, 454: 903. [10] Huang N E, Shen Z, Long S R. Annual Review of Fluid Mechanics, 1999, 31: 417. [11] Bao L, Dai P H. Journal of Systems Engineering, 1999, 14(4): 338.