Abstract：The molecular recognition of fungicide of kresoxim-methyl with β-cyclodextrin(β-CD) , methyl-β-cyclodextrin(RAMEB)and hydroxypropyl-β-cyclodextrin(RAMEB) was investigated by using UV-Vis spectroscopy analysis. The effect of temperature and polarity of solvent on the recognition interaction was studied. The driving force and the possible structure of the inclusion complexes were also discussed. The results presented that they formed inclusion complexes with a stoichiometry of 1∶1, and the formation constant of inclusion complexes was in the order of KHP-β-CD>Kβ-CD>KRAMEB at 298.15 K. Elevation of the temperature triggered a decrease in stability of the inclusion complexes and the value of Kβ-CD was the biggest at ≥303.15 K . The formation constant reduced sharply with the decreasing polarity of the solvent. The standard molar Gibbs energies, enthalpies and entropies were all negative. All the results indicated that the association of the guest molecule with β-CD was favored by enthalpy changes, and hydrophobicity and hydrogen bond interaction were main driving forces for the inclusion reaction. Our findings provided an important proof for the use of inclusion complexes of kresoxim-methyl with CDs.
肖玉梅,吴燕华,刘吉平,李艳芳,李楠*,覃兆海*. β-环糊精及其衍生物对杀菌剂醚菌酯的分子识别作用的研究[J]. 光谱学与光谱分析, 2008, 28(10): 2370-2374.
XIAO Yu-mei,WU Yan-hua,LIU Ji-ping,LI Yan-fang,LI Nan*,QIN Zhao-hai*. Study on the Molecular Recognization of Fungicide of Kresoxim-Methyl with β-cyclodextrin and Its Derivatives. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2008, 28(10): 2370-2374.
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