Abstract：To improve the signal-to-noise ratio (SNR) of the dynamic spectrum (DS) data and to increase the stability of the model and the prediction accuracy, the harmonic waves of DS data were introduced into DS method. Sixty samples were determined as the research objects according to the quality of the pulse wave and the distribution of the harmonic waves after further analysis of 110 volunteers’ data acquired in vivo. This paper took whether adding the energy of harmonic waves into the DS data as the division standard to generate two groups. BP artificial neural network was used to establish the calibration model of subjects’ hemoglobin values against DS. The correlation coefficients of the predicted values and the true values in experimental group, containing the energy of harmonic waves, was 0.91, much higher than 0.80 in the control group. Other indexes were all improved too. The results showed that the modified method can enhance the SNR of DS method and accelerate the development of noninvasive blood components measurement based on DS method.
Key words：Dynamic spectrum;Hemoglobin;Noninvasive measurement;Signal-to-noise ratio
李 刚，王慧泉，赵 喆，林 凌 . 谐波分量提高动态光谱法无创血液成分检测精度 [J]. 光谱学与光谱分析, 2010, 30(09): 2385-2389.
LI Gang, WANG Hui-quan, ZHAO Zhe, LIN Ling . Increasing the Precision of the Noninvasive Blood Components Measurement Based on DS Method Using Harmonic Waves . SPECTROSCOPY AND SPECTRAL ANALYSIS, 2010, 30(09): 2385-2389.
[1] Lü Li-na, LI Qing-bo, ZHANG Guang-jun. Journal of Infrared Millimeter and Terahertz Waves, 2009, 30(11): 1191. [2] Petrov Y Y, Prough D S, Petrova I, et al. Progress in Biomedical Optics and Imaging-Proceedings of SPIE, 2007, 6437：34750. [3] Manohar S，Vaartjes S E，van Hespen J C G, et al. Optics Express, 2007, 15: 12277. [4] Gowda A, McNichols R J, Fossum T W, et al. Proceedings of SPIE-The International Society for Optical Engineering, 2001, 4263: 11. [5] LUO Yun-han(罗云瀚). Laser & Infrared(激光与红外), 2008, 38(5): 465. [6] Zhang Xi-qin，Yeo Joon Hock. Progress in Biomedical Optics and Imaging-Proceedings of SPIE, 2009, 7186：11860R. [7] GAO Chang-hao(高昌浩). Contemporary Medicine(现代医学)，2009, 15: 20. [8] Matthew E Eames，Hamid Dehghani. Optics Express, 2008, 16(22): 17780. [9] Jobsis F F. Science, 1977, 198(4323): 1264. [10] Gibson Adam，Dehghani Hamid. Phil. Trans. R. Soc. A，2009, 367: 3055. [11] LI Gang, WANG Yan, LIN Ling, et al(李 刚，王 焱，林 凌，等). Life Science Instruments(生命科学仪器)，2004，2(5): 33. [12] LI Gang, LI Hai-lan(李 刚, 李海兰). Journal of Test and Measurement Technology(测试技术学报)，2006, 20: 108. [13] LIN Ling, YANG Ying-chao, LI Gang(林 凌，杨英超，李 刚). Spectroscopy and Spectral Analysis(光谱学与光谱分析), 2009, 29(10): 2769. [14] Li C W, Hu R Q. 7th IEEE International Conference on Bioinformatics and Bioengineering, Boston, 3007. 1168. [15] Sun Yuzhu,Song Xingfu, Wang Jin, et al. Journal of Crystal Growth，2009, 311(23-24): 4714.
