1. Institute of Laser Life Science, South China Normal University, Guangzhou 510631, China 2. Fujian Provincial Key Laboratory of Photonic Technology, Fujian Normal University, Fuzhou 350007, China 3. First Affiliated Hospital of Sun Yat-Sen University of Medical Sciences, Guangzhou 510080, China 4. Department of Surgery, Guangdong College of Pharmacy, Guangzhou 510224, China
Abstract：A double-integrating-spheres and IAD method were used to study the differences in the optical penetration depths (OPDs) and light attenuation (LA) native and coagulated human liver tumors and liver tissues at the wavelengths of 680, 720, 780, 810, 850 and 890 nm of Ti:Sapphire laser. The results of measurement showed that the OPDs for native and coagulated human liver tumors and liver tissues at six different wavelengths obviously increase with increasing laser wavelength, the OPDs of coagulated human liver tumors and liver tissues at six different wavelengths were significantly smaller than that of native human liver tumors and liver tissues at the same wavelength respectively (P＜0.05), and the OPDs of native and coagulated human liver tumors at six different wavelengths were significantly bigger than that of native and coagulated human liver tissues at the same wavelength respectively (P＜0.05). The LA for native and coagulated human liver tumors and liver tissues at six different wavelengths obviously decreases with increasing laser wavelength, and the LA for coagulated human liver tumors and liver tissues at six different wavelengths is significantly bigger than that for native human liver tumors and liver tissues at the same wavelength respectively (P＜0.05). The LA for native and coagulated human liver tumors at six different wavelengths is significantly bigger than that for native and coagulated human liver tissue at the same wavelength respectively (P＜0.05).
Key words：Human liver tumors and normal liver tissues;Ti:Sapphire laser;Thermal coagulation;Light attenuation characteristics;Optical penetration depth
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