Fourier Transform Infrared Spectroscopy Study on Normal and Malignant Tissues of Cervix
LI Wei-xiu1, ZHENG Quan-qing1*, WANG Ping2, LI Yan-qin1, CHEN Guang-hua1
1. Medical College of Xi’an Jiaotong University, Xi’an 710061, China 2. Department of Gynecologic Oncology, Cancer Hospital of Shaanxi Province, Xi’an 710061, China
Abstract：Fourier transform infrared spectroscopy (FTIR) was used to investigate 35 cervical tissues , including 17 squamous cell carcinoma of cervical samples, and 5 adenocarcinoma of cervical samples, 13 normal cervical samples. The results show that there are 18 spectral bands with highly appearance percentage(＞80%)in these three types of tissues, and these spectral bands may be the characteristic infrared spectra bands for cervical tissues ; Some of relative absorbance ratios are statistically significant(p＜0.05) among these three types of tissues. These differences of relative absorbance ratios are mainly centered at 1 080, 1 238, 1 314, 1 339, 1 397, 1 454, 1 541, 1 647, 2 854, 2 873, 2 926, and 2 958 cm-1. The present results indicate that FTIR can be used to distinguish these three types of tissues. The utilization of FTIR spectra in cervical tissues is expected to be a hopeful method in cervical cancer screening and clinical diagnosis in the future.
李炜修1,郑全庆1*,王平2,李燕琴1,陈广华1 . 宫颈正常与宫颈癌组织傅里叶变换红外光谱的初步研究[J]. 光谱学与光谱分析, 2006, 26(10): 1833-1837.
LI Wei-xiu1, ZHENG Quan-qing1*, WANG Ping2, LI Yan-qin1, CHEN Guang-hua1 . Fourier Transform Infrared Spectroscopy Study on Normal and Malignant Tissues of Cervix. SPECTROSCOPY AND SPECTRAL ANALYSIS, 2006, 26(10): 1833-1837.
